The use of recent advances in electron microscopy to study ribosome structure Event as iCalendar

03 April 2017


Venue: Owen G Glenn Building, room 260-092

Location: OGGB, Grafton Road

Cost: Free, all welcome

Contact info: Ted Baker

Contact email:

Recent advances in in electron microscopy have made it possible to reach ~3 Å resolution for biological macromolecules using single-particle electron microscopy. This has, for the first time, made it possible to obtain atomic models of these molecules without the need for crystals and with very small amounts of heterogeneous samples. Dr Venki Ramakrishnan will discuss how his laboratory has used these advances to determine the structures of the yeast and human mitochondrial ribosomes. These structures reveal interesting differences showing how the two species have not only diverged from their putative bacterial ancestor, but also from each other.

The School of Biological Sciences and Maurice Wilkins Centre are delighted to be hosting Dr Venki Ramakrishnan for this special research seminar. Dr Ramakrishnan, an eminent structural biologist, received the Nobel Prize in Chemistry in 2009 for his work on the structure and function of the ribosome, and was knighted in 2012. He is the current President of the Royal Society of London, and is a Group Leader and Deputy Director at the Medical Research Council Laboratory of Molecular Biology, UK.